Safety of Percutaneous Dilatational Tracheostomy in Critically Ill Patients with Liver Cirrhosis.

INTRODUCTION: Percutaneous Dilatational Tracheostomy (PDT) is a safe and cost-effective alternative to surgical tracheostomy. Cirrhotic patients often require ICU admission and prolonged mechanical ventilation. Patients with liver cirrhosis (LC) are known to have coagulopathy and relatively safe and simple procedures such as tracheostomy may be associated with high complication rates, specifically high bleeding rates. Current guidelines are unable to make a specific recommendation on the safety of PDT among cirrhotic patients. We aimed to evaluate the safety of PDT in critically ill patients with LC. METHODS: A retrospective chart review identified critically ill patients who underwent PDT between 1/2012 and 3/2023. The study group was defined as all patients with a diagnosis of LC. The primary outcome was early (7-day) bleeding, categorized as minor or major. Secondary outcomes were PDT-related and 30-day all-cause mortality. Propensity score matching was performed to adjust the imbalances between the groups. RESULTS: A total of 1,628 were included in the analysis. Thirty-three of them (2.0%) had LC. In the LC group, only one patient (3.0%, 95% CI 0.0%-15.8%) developed early bleeding. Intra-operative, early, late bleeding, and PDT-related mortality rates did not differ significantly between those with LC and those without. CONCLUSION: This retrospective cohort study indicates that PDT can be safely performed in critically ill cirrhotic patients, without significantly increasing the risk of bleeding complications.

Percutaneous Dilatational Tracheostomy in Patients Receiving Dual Antiplatelet Therapy.

This cohort study investigates bleeding and mortality outcomes of percutaneous dilatational tracheostomy among critically ill patients receiving dual antiplatelet therapy.

Impact of radiological surveillance for major blood vessels on complications of percutaneous dilatational tracheostomy: A retrospective cohort study.

PURPOSE: Percutaneous dilatational tracheostomy (PDT) is the preferred method for managing long-term ventilator-dependent patients in ICUs. This study aimed to evaluate the association between preprocedural screening (ultrasound Doppler [USD] or computed tomography [CT]) for major neck blood vessels and complications in ICU patients undergoing PDT. MATERIALS AND METHODS: This was a retrospective cohort study of patients who underwent PDT between 2012 and 2023 at a tertiary referral center. We performed a multivariable analysis and created a propensity-matched cohort. The primary outcome was bleeding within the first seven days after PDT. Secondary outcomes included early and late PDT complications and PTD-related mortality. RESULTS: A total of 1766 consecutive critically ill patients hospitalized at a tertiary academic hospital were evaluated for PDT. Of these, 881 (49.9 %) underwent only physical examination before PDT, while 885 (50.1 %) underwent additional imaging (CT/USD). A higher proportion of patients in the imaging group were referred to open surgery due to suspected major blood vessels interfering with the procedure (6.2 % vs. 3.0 %, p = 0.001). Among the 1685 patients who underwent PDT, there was no significant difference in the rate of early bleeding between the physical examination group and the imaging group (4.6 % vs. 6.3 %, p = 0.12). Similarly, the overall early complication rates (5.5 % vs. 7.6 %, p = 0.08), late complication rates (1.6 % vs. 2.2 %, p = 0.42), and PDT-related mortality rates (0.7 % vs. 0.6 %, p = 0.73) did not exhibit significant differences between the two groups. In a propensity score-matched cohort, results remained consistent. CONCLUSIONS: Physical examination can effectively identify major neck blood vessels without increasing the risk of bleeding during and after PDT.

Corrigendum to "Clinical Outcomes of Critically Ill Patients Using Inhaled Nitric Oxide (iNO) during Intrahospital Transport".

[This corrects the article DOI: 10.1155/2021/6633210.].

Clinical Outcomes of Critically Ill Patients Using Inhaled Nitric Oxide (iNO) during Intrahospital Transport.

Critically ill patients with severe hypoxemia are often treated in the intensive care unit (ICU) with inhaled nitric oxide (iNO). These patients are at higher risk when they require intrahospital transportation. In this study, we collected clinical and laboratory data from 221 patients who were hospitalized in the general ICU and treated with iNO at Soroka Medical Center, Israel, between January 2010 and December 2019. We retrospectively compared the 65 patients who received iNO during intrahospital transportation to the 156 patients who received iNO without transportation. Among critically ill patients who were transported while being administered iNO, only one patient had an adverse event (atrial fibrillation) on transport. We found that maximal iNO dosage during ICU stay, duration of mechanical ventilation, and percent of vasopressor support were the only independent risk factors for ICU mortality in both study groups. No difference in primary outcome of ICU mortality rate was found between the critically ill patients treated with iNO during intrahospital transportation and those who were treated with iNO but not transported during the ICU stay. We anticipate that this study will advise clinical decision-making in the ICU, especially when treating patients who are administered iNO.

[CLINIC BLOOD PRESSURE MONITORING AS A PREDICTOR OF MASKED HYPERTENSION].

INTRODUCTION: Masked hypertension is strongly linked to morbidity and mortality. The phenomenon poses a challenge to physicians due to the difficult diagnosis. Recent studies have shown that the incidence may occur in 8.8% -16.6% of the population and up to 30.4% among people with borderline blood pressure. OBJECTIVES: To examine the prevalence of masked hypertension in the Israeli population and the clinic blood pressure status as a predictor of masked hypertension. METHODS: Interviewees were randomly recruited from among passers-by at Assuta Hospital in Ashdod. Those who were found to have normal and normal-high blood pressure ranges were included in the study. Ambulatory blood pressure monitoring was performed, and anthropometric measures were assessed. A statistical analysis compared groups according to their blood pressure clinical and ambulatory blood pressure categories. RESULTS: A total of 35 participants were included in this research. Masked hypertension was found among 35.3% of patients with normal range blood pressure and 27.7% of those in the borderline range. Significant differences were found between the normotensive group and the masked hypertension group in BMI, waist circumference, and clinical category of clinic diastolic blood pressure. CONCLUSIONS: A third of those with in-clinic normal blood pressure suffer from masked hypertension. Borderline in-clinic diastolic blood pressure is significantly associated with masked hypertension. DISCUSSION: This study presents higher masked hypertension rates than previously reported, the difference may be explained by differences in the nature and the lifestyle of the study population. The high incidence of the phenomenon indicates the need for further investigation of patients with in-clinic normal and borderline blood pressure.

[RESISTIVE INDEX - A POSSIBLE SUBTLE INDEX OF KIDNEY DYSFUNCTION IN PRE-HYPERTENSIVE PATIENTS].

INTRODUCTION: The phenomenon of "masked hypertension" is a diagnostic challenge for physicians. The renal resistance index is a radiological index that expresses damage to the renal blood vessels. The literature regarding the relationship between the renal resistance index and primary kidney disease (as a cause of hypertension) or kidney disease as a result of hypertension is low and limited. OBJECTIVES: The aim of this study is to examine the reliability of the renal resistive index as a means of detecting masked hypertension. METHODS: Respondents were recruited at random, those who were found within normal and normal-high blood pressure ranges were included in the study. A renal ultrasound and ambulatory blood pressure monitoring were performed, and anthropometric measures were assessed. A statistical analysis compared groups according to their blood pressure clinical category and the presence of masked hypertension versus normal. RESULTS: No significant difference was found between the study groups in the renal resistance indices. CONCLUSIONS: The renal resistive index is not an appropriate tool for assessing the presence of masked hypertension in patients with in-clinic pre-hypertension. DISCUSSION: The results of the study were consistent with previous studies that question the clinical use of the renal resistive index. There is no room for using the renal resistive index as a tool to assess the likelihood of masked hypertension in patients with in-clinic pre-hypertension.